Clinical experience in T cell deficient patients
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چکیده
منابع مشابه
Clinical experience in T cell deficient patients
T cell disorders have been poorly understood until recently. Lack of knowledge of underlying molecular mechanisms together with incomplete data on long term outcome have made it difficult to assess prognosis and give the most effective treatment. Rapid progress in defining molecular defects, improved supportive care and much improved results from hematopoietic stem cell transplantation (HSCT) n...
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GATA binding protein 2 (GATA2) deficiency is a rare disorder of hematopoiesis, lymphatics, and immunity caused by spontaneous or autosomal dominant mutations in the GATA2 gene. Clinical manifestations range from neutropenia, lymphedema, deafness, to severe viral and mycobacterial infections, bone marrow failure, and acute myeloid leukemia. Patients also present with monocytopenia, dendritic cel...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Clinical Immunology
سال: 2010
ISSN: 1710-1492
DOI: 10.1186/1710-1492-6-9